BIOMICs (Genómica, Transcriptómica y Epigenómica)

  • Cáncer
    • Estudio de los factores genéticos y epigenéticos que intervienen en la susceptibilidad a desarrollar cáncer, así como en su diagnóstico y respuesta a los diferentes tratamientos.
  • Neurodegeneración
    • Estudio de los factores genéticos y epigenéticos que intervienen en la susceptibilidad a diversas enfermedades neurodegenerativas, así como en su diagnóstico y respuesta a los diferentes tratamientos.

FELIX OLASAGASTI ARSUAGA

Facultad de Farmacia

MARTA ARROYO IZAGA

Facultad de Farmacia

MIRIAM BAETA BAFALLUY

Centro de Investigación Lascaray (UPV-EHU)

EVA GRANIZO RODRÍGUEZ

Centro de Investigación Lascaray (UPV-EHU)

CATERINA RAFFONE

Centro de Investigación Lascaray (UPV-EHU)

MAITE ÁLVAREZ ÁLVAREZ

Centro de Investigación Lascaray (UPV-EHU)

BELÉN NAVARRO LÓPEZ

Facultad de Farmacia

DANIEL AZKARATE IGARZA

Centro de investigación Lascaray Ikergunea

A genetic history of the Balkans from Roman frontier to Slavic migrations.
Olalde, I., Carrión, P., Mikic, I., Rohland, N., Mallick, S., Lazaridis, I., Mah, M., Korac, M., Golubovic, S., Petkovic, S., Miladinovic-Radmilovic, N., Vulovic, D., Alihodžic, T., Ash, A., Baeta, M., Bartík, J., Bedic, null, Bilic, M., Bonsall, C., Buncic, M., Bužanic, D., Caric, M., Cataj, L., Cvetko, M., Drnic, I., Dugonjic, A., Ðukic, A., Ðukic, K., Farkaš, Z., Jelínek, P., Jovanovic, M., Kaic, I., Kalafatic, H., Krmpotic, M., Krznar, S., Lelekovic, T., M. de Pancorbo, M., Matijevic, V., Miloševic Zakic, B., Osterholtz, A.J., Paige, J.M., Tresic Pavicic, D., Premužic, Z., Rajic Šikanjic, P., Rapan Papeša, A., Paraman, L., Sanader, M., Radovanovic, I., Roksandic, M., Šefcáková, A., Stefanovic, S., Teschler-Nicola, M., Toncinic, D., Zagorc, B., Callan, K., Candilio, F., Cheronet, O., Fernandes, D., Kearns, A., Lawson, A.M., Mandl, K., Wagner, A., Zalzala, F., Zettl, A., Tomanovic, null, Keckarevic, D., Novak, M., Harper, K., McCormick, M., Pinhasi, R., Grbic, M., Lalueza-Fox, C., Reich, D..

Cell, 186, 5472-54859. 2023
Association between nutrient intake related to the one-carbon metabolism and colorectal cancer risk: a case–control study in the Basque Country.
Martín-Fernández-de-Labastida, S., Alegria-Lertxundi, I., De Pancorbo, M.M., Arroyo-Izaga, M..

EUROPEAN JOURNAL OF NUTRITION, 62, 3181-3191. 2023
Cell Patterning Technology on Polymethyl Methacrylate through Controlled Physicochemical and Biochemical Functionalization.
Azuaje-Hualde, E., Komen, J., Alonso-Cabrera, J.A., van den Berg, A., De Pancorbo, M.M., van der Meer, A.D., Benito-Lopez, F., Basabe-Desmonts, L..

BIOSENSORS-BASEL, 13, . 2023
m6A levels and expression of its modification genes show significant differences in breast cancer molecular subtypes.
Kleinbielen, Tamara, Olasagasti, Felix, Beristain, Elena, Viguri-Diaz, Amparo, Guerra-Merino, Isabel, Garcia-Orad, Africa, de Pancorbo, Marian M..

Genes & Diseases, 10, 1751-1754. 2023
On the Y chromosome of Chennai, Tamil Nadu and the Indian subcontinent.
Luis, J.R., Palencia-Madrid, L., Deshpande, K., Alfonso-Sanchez, M.A., Peña, J.A., De Pancorbo, M.M., Garcia-Bertrand, R., Herrera, R.J..

Gene, 859, 147175. 2023
Prevalence and Predictors of Food Insecurity among Students of a Spanish University during the COVID-19 Pandemic: FINESCOP Project at the UPV/EHU.
Gonzalez-Perez, Raquel, Garcia-Iruretagoyena, Laura, Martinez-Perez, Naiara, Telleria-Aramburu, Nerea, Telletxea, Saioa, Padoan, Sonia, Torheim, Liv Elin, Arroyo-Izaga, Marta.

Nutrients, 15, . 2023
Influence of methyl donor nutrients as epigenetic regulators in colorectal cancer: A systematic review of observational studies.
Chávez-Hidalgo, L.P., Martín-Fernández-de-Labastida, S., De Pancorbo, M.M., Arroyo-Izaga, M..

WORLD JOURNAL OF GASTROENTEROLOGY, 29, 1219-1234. 2023
Development and validation of a new multiplex for upgrading Y-STRs population databases from 12 to 23 markers and its forensic casework application.
Navarro-López, B., Baeta, M., Granizo-Rodríguez, E., Moreno-López, O., Kleinbielen, T., Ferragut, J.F., Picornell, A., De Pancorbo, M.M..

SCIENTIFIC REPORTS, 12, . 2022
High levels of HDAC expression correlate with microglial aging..
Auzmendi-Iriarte, Jaione, Moreno-Cugnon, Leire, Saenz-Antonanzas, Ander, Grassi, Daniela, de Pancorbo, Marian M., Arevalo, Maria-Angeles, Wood, Ian C., Matheu, Ander.

EXPERT OPINION ON THERAPEUTIC TARGETS, 26, 1-12. 2022
In silico identification and in vitro expression analysis of breast cancer-related m(6)A-SNPs.
Kleinbielen, Tamara, Olasagasti, Felix, Azcarate, Daniel, Beristain, Elena, Viguri-Diaz, Amparo, Guerra-Merino, Isabel, Garcia-Orad, Africa, de Pancorbo, Marian M..

EPIGENETICS, 17, 2144-2156. 2022
On-campus food purchase behaviors, choice determinants, and opinions on food availability in a Spanish university community.
Martinez-Perez, N., Telleria-Aramburu, N., Insúa, P., Hernández, I., Telletxea, S., Ansotegui, L., Rebato, E., Basabe, N., De Pancorbo, M.M., Rocandio, A., Arroyo-Izaga, M..

Nutrition, 103-104, . 2022
Genetic polymorphisms of 17 X-STR loci in two Tunisian populations from Sousse and Makthar.
Mejri, A., Baeta, M., Al-Haj-Taib, R., Herrera, R.J., Benammar-Elgaaied, A., De Pancorbo, M.M., Fadhlaoui-Zid, K..

ANNALS OF HUMAN BIOLOGY, , . 2022
Paper based microfluidic platform for single-step detection of mesenchymal stromal cells secreted VEGF.
Azuaje-Hualde, E., De Pancorbo, M.M., Benito-Lopez, F., Basabe-Desmonts, L..

ANALYTICA CHIMICA ACTA, 1199, . 2022
Genetic characterization of populations in the Marquesas Archipelago in the context of the Austronesian expansion.
Tätte, K., Metspalu, E., Post, H., Palencia-Madrid, L., Luis, J.R., Reidla, M., Tamm, E., Ilumäe, A.-M., De Pancorbo, M.M., Garcia-Bertrand, R., Metspalu, M., Herrera, R.J..

SCIENTIFIC REPORTS, 12, . 2022
Nutritional quality and carbon footprint of university students' diets: results from the EHU12/24 study.
Telleria-Aramburu, N, Bermudez-Marin, N, Rocandio, AM, Telletxea, S, Basabe, N, Rebato, E, Arroyo-Izaga, M.

PUBLIC HEALTH NUTRITION, 25, 183-195. 2022
ANALYSIS OF REDUCED SIZE STRAMPLICONS AS TOOLS FOR THE STUDY OF DEGRADED DNA.
Baeta, M., Nuñez, C., González-Andrade, F., Gascón, S., Martínez-Jarreta, B..

Forensic Genetics Research Progress, , 133-150. 2022
DOI:
Post-Austronesian migrational wave of West Polynesians to Micronesia.
Palencia-Madrid, L., Baeta, M., Kleinbielen, T., Toro-Delgado, N., Villaescusa, P., Sanchez-Bustamante, E., De Pancorbo, M.M., Luis, J.R., Ware, K.E., Somarelli, J.A., Garcia-Bertrand, R., Herrera, R.J..

Gene, 823, . 2022
'Among his fellows cast': A histotaphonomic investigation into the impact of the Black Death in England.
Hemer, KA, Booth, TJ, Raffone, C, Mann, C, Corkhill, CL, Willmott, H.

JOURNAL OF ARCHAEOLOGICAL SCIENCE-REPORTS, 39, . 2021
Phylogeographic review of Y chromosome haplogroups in Europe..
Navarro-López B, Granizo-Rodríguez E, Palencia-Madrid L, Raffone C, Baeta M, de Pancorbo MM.

INTERNATIONAL JOURNAL OF LEGAL MEDICINE, 135, 1675-1684. 2021
Intrinsic and extrinsic factors that may influence DNA preservation in skeletal remains: A review..
Raffone C, Baeta M, Lambacher N, Granizo-Rodríguez E, Etxeberria F, de Pancorbo MM.

FORENSIC SCIENCE INTERNATIONAL, 325, 110859-110859. 2021
Continuous monitoring of cell transfection efficiency with micropatterned substrates.
Azuaje-Hualde, E, Rosique, M, Calatayud-Sanchez, A, Benito-Lopez, F, de Pancorbo, MM, Basabe-Desmonts, L.

BIOTECHNOLOGY AND BIOENGINEERING, 118, 2626-2636. 2021
The Ami and Yami aborigines of Taiwan and their genetic relationship to East Asian and Pacific populations.
Tatte, K, Metspalu, E, Post, H, Palencia-Madrid, L, Luis, JR, Reidla, M, Rea, A, Tamm, E, Moding, EJ, de Pancorbo, MM, Garcia-Bertrand, R, Metspalu, M, Herrera, RJ.

EUROPEAN JOURNAL OF HUMAN GENETICS, 29, 1092-1102. 2021
Association of LCT-13910C>T polymorphism and hip fracture in a cohort of older adult population from Northern Spain.
Kleinbielen, Tamara, Palencia-Madrid, Leire, Garcia-Ibarbia, Carmen, Ortiz, Fernando, Riancho, Jose A., Pancorbo, Marian M. de.

Gene, 783, 145560-145560. 2021
Design and Validation of a Process Based on Cationic Niosomes for Gene Delivery into Novel Urine-Derived Mesenchymal Stem Cells..
Vado Y, Puras G, Rosique M, Martin C, Pedraz JL, Jebari-Benslaiman S, de Pancorbo MM, Zarate J, Perez de Nanclares G.

Pharmaceutics, 13, . 2021
The Y chromosome of autochthonous Basque populations and the Bronze Age replacement.
Luis, JR, Palencia-Madrid, L, Mendoza, VC, Garcia-Bertrand, R, de Pancorbo, MM, Herrera, RJ.

SCIENTIFIC REPORTS, 11, . 2021
Study of 17 X-STRs in Native American and Mestizo populations of Central America for forensic and population purposes.
Baeta, Miriam, Prieto-Fernandez, Endika, Nunez, Carolina, Kleinbielen, Tamara, Villaescusa, Patricia, Palencia-Madrid, Leire, Alvarez-Gila, Oscar, Martinez-Jarreta, Begona, de Pancorbo, Marian M..

INTERNATIONAL JOURNAL OF LEGAL MEDICINE, 135, 1773-1776. 2021
A Y-chromosomal survey of Ecuador 's multi-ethnic population reveals new insights into the tri-partite population structure and supports an early Holocene age of the rare Native American founder lineage C3-MPB373.
Villaescusa, P, Seidel, M, Nothnagel, M, Pinotti, T, Gonzalez-Andrade, F, Alvarez-Gila, O, de Pancorbo, MM, Roewer, L.

FORENSIC SCIENCE INTERNATIONAL-GENETICS, 51, . 2021
Effect of a genetic polymorphism in SREBP1 on fatty acid composition and related gene expression in subcutaneous fat tissue of beef cattle breeds.
Gamarra, D, Aldai, N, Arakawa, A, Pancorbo, MM, Taniguchi, M.

ANIMAL SCIENCE JOURNAL, 92, . 2021
Genetic Characterization of the Local Pirenaica Cattle for Parentage and Traceability Purposes..
Gamarra D, Taniguchi M, Aldai N, Arakawa A, Lopez-Oceja A, de Pancorbo MM.

ANIMALS, 10, . 2020
A Genome-Wide Study of Single-Nucleotide Polymorphisms in MicroRNAs and Further In Silico Analysis Reveals Their Putative Role in Susceptibility to Late-Onset Alzheimer's Disease..
Herrera-Espejo, Soraya, Santos-Zorrozua, Borja, Alvarez-Gonzalez, Paula, Martin-Guerrero, Idoia, M de Pancorbo, Marian, Garcia-Orad, Africa, Lopez-Lopez, Elixabet.

MOLECULAR NEUROBIOLOGY, 58, 55-64. 2020
Naked eye Y amelogenin gene fragment detection using DNAzymes on a paper-based device.
Azuaje-Hualde, E, Arroyo-Jimenez, S, Garai-Ibabe, G, de Pancorbo, MM, Benito-Lopez, F, Basabe-Desmonts, L.

ANALYTICA CHIMICA ACTA, 1123, 1-8. 2020
Food groups, diet quality and colorectal cancer risk in the Basque Country..
Alegria-Lertxundi I, Aguirre C, Bujanda L, Fernández FJ, Polo F, Ordovás JM, Etxezarraga MC, Zabalza I, Larzabal M, Portillo I, de Pancorbo MM, Garcia-Etxebarria K, Rocandio AM, Arroyo-Izaga M.

WORLD JOURNAL OF GASTROENTEROLOGY, 26, 4108-4125. 2020
Optical Single Cell Resolution Cytotoxicity Biosensor Based on Single Cell Adhesion Dot Arrays.
Garcia-Hernando, M, Calatayud-Sanchez, A, Etxebarria-Elezgarai, J, de Pancorbo, MM, Benito-Lopez, F, Basabe-Desmonts, L.

ANALYTICAL CHEMISTRY, 92, 9658-9665. 2020
Validation of a 52-mtSNP minisequencing panel for haplogroup classification of forensic DNA samples..
Palencia-Madrid L, Vinueza-Espinosa D, Baeta M, Rocandio AM, de Pancorbo MM.

INTERNATIONAL JOURNAL OF LEGAL MEDICINE, 134, 929-936. 2020
Single nucleotide polymorphisms associated with susceptibility for development of colorectal cancer: Case-control study in a Basque population..
Alegria-Lertxundi I, Aguirre C, Bujanda L, Fernández FJ, Polo F, Ordovás JM, Etxezarraga MC, Zabalza I, Larzabal M, Portillo I, de Pancorbo MM, Palencia-Madrid L, Rocandio AM, Arroyo-Izaga M.

PLOS ONE, 14, 225779-225779. 2019
Forensic application of a mtDNA minisequencing 52plex: Tracing maternal lineages in Spanish Civil War remains.
Baeta, M, Garcia-Rey, S, Palencia-Madrid, L, Raffone, C, de Pancorbo, MM.

FORENSIC SCIENCE INTERNATIONAL GENETICS SUPPLEMENT SERIES, 7, 457-458. 2019
CYT B L15601 and H15748 primers for genetic identification of cetacean species.
Lopez-Oceja, A, Lekube, X, Ruiz, L, Mujika-Alustiza, JA, de Pancorbo, MM.

FORENSIC SCIENCE INTERNATIONAL GENETICS SUPPLEMENT SERIES, 7, 771-772. 2019
Genetic analysis of 12 X-chromosomal STRs an autochthonous population of Southeast Spain.
Susana, JM, Celia, G, Ester, L, Miriam, B, Eladio, B, Marian, MD.

FORENSIC SCIENCE INTERNATIONAL GENETICS SUPPLEMENT SERIES, 7, 482-484. 2019
NOS1AP SNPs related to sudden arrhythmic death syndrome.
Kleinbielen, T, Hernandez-Sierra, M, Prieto-Fernandez, E, Olasagasti, F, Sevillano, R, de Pancorbo, MM.

FORENSIC SCIENCE INTERNATIONAL GENETICS SUPPLEMENT SERIES, 7, 569-571. 2019
The impact of haplogroup R1b-DF27 in Hispanic admixed populations from Latin America.
Villaescusa, P, Blazquez, P, Martinez-Jarreta, B, Jimenez, S, Alvarez-Gila, O, de Pancorbo, MM.

FORENSIC SCIENCE INTERNATIONAL GENETICS SUPPLEMENT SERIES, 7, 488-490. 2019
Updating data on the genetic identification of bone remains of victims of the Spanish Civil War.
Baeta, M, Nunez, C, Raffone, C, Granizo, E, Palencia-Madrid, L, Cardoso, S, Etxeberria, F, Herrasti, L, de Pancorbo, MM.

FORENSIC SCIENCE INTERNATIONAL GENETICS SUPPLEMENT SERIES, 7, 582-584. 2019
A unique common ancestor introduced P301L mutation in MAPT gene in frontotemporal dementia patients from Barcelona (Baix Llobregat, Spain).
Palencia-Madrid, L, Sanchez-Valle, R, de Retana, IF, Borrego, S, Grau-Rivera, O, Rene, R, Hernandez, I, Almenar, C, Rossi, G, Caroppo, P, Redaelli, V, Le Ber, I, Camuzat, A, Brice, A, Antonell, A, Balasa, M, Gelpi, E, Llado, A, de Pancorbo, MM.

NEUROBIOLOGY OF AGING, 84, . 2019
Lipid-Assisted Polymerization of Nucleotides.
Olasagasti, F, Rajamani, S.

LIFE-BASEL, 9, . 2019
Extracellular matrix protein microarray-based biosensor with single cell resolution: Integrin profiling and characterization of cell-biomaterial interactions.
Gonzalez-Pujana, A, Santos-Vizcaino, E, Garcia-Hernando, M, Hernaez-Estrada, B, de Pancorbo, MM, Benito-Lopez, F, Igartua, M, Basabe-Desmonts, L, Hernandez, RM.

SENSORS AND ACTUATORS B-CHEMICAL, 299, . 2019
A Statistical Method to Enhance the Analysis of the Differences Among High-Resolution Melting (HRM) Curves of PCR-Amplified DNA Fragments.
Ibarrondo, O, Lopez-Oceja, A, Baeta, M, de Pancorbo, MM.

JOURNAL OF FOOD SCIENCE, 84, 2719-2728. 2019
Genome-wide association analysis of dementia and its clinical endophenotypes reveal novel loci associated with Alzheimer's disease and three causality networks: The GR@ACE project.
Moreno-Grau, S, de Rojas, I, Hernandez, I, Quintela, I, Montrreal, L, Alegret, M, Hernandez-Olasagarre, B, Madrid, L, Gonzalez-Perez, A, Maronas, O, Rosende-Roca, M, Mauleon, A, Vargas, L, Lafuente, A, Abdelnour, C, Rodriguez-Gomez, O, Gil, S, Santos-Santos, MA, Espinosa, A, Ortega, G, Sanabria, A, Perez-Cordon, A, Canabate, P, Moreno, M, Preckler, S, Ruiz, S, Aguilera, N, Pineda, JA, Macias, J, Alarcon-Martin, E, Sotolongo-Grau, O, Marquie, M, Monte-Rubio, G, Valero, S, Benaque, A, Clarimon, J, Bullido, MJ, Garcia-Ribas, G, Pastor, P, Sanchez-Juan, P, Alvarez, V, Pinol-Ripoll, G, Garcia-Alberca, JM, Royo, JL, Franco, E, Mir, P, Calero, M, Medina, M, Rabano, A, Avila, J, Antunez, C, Real, LM, Orellana, A, Carracedo, A, Saez, ME, Tarraga, L, Boada, M, Ruiz, A, Abdelnour, C, Aguilera, N, Alarcon, E, Alegret, M, Benaque, A, Boada, M, Buendia, M, Canabate, P, Carracedo, A, Corbaton, A, de Rojas, I, Diego, S, Espinosa, A, Gailhajenet, A, Gonzalez, PG, Gil, S, Guitart, M, Perez, AG, Ibarria, M, Lafuente, A, Macias, J, Maronas, O, Martin, E, Martinez, MT, Marquie, M, Mauleon, A, Monte-Rubio, G, Montrreal, L, Moreno-Grau, S, Moreno, M, Orellana, A, Ortega, G, Pancho, A, Peleja, E, Perez-Cordon, A, Pineda, JA, Preckler, S, Quintela, I, Real, LM, Rodriguez-Gomez, O, Rosende-Roca, M, Ruiz, A, Ruiz, S, Saez, ME, Sanabria, A, Santos-Santos, MA, Serrano-Rios, M, Tarraga, L, Valero, S, Vargas, L, Adarmes-Gomez, AD, Alarcon-Martin, E, Alvarez, I, Alvarez, V, Amer-Ferrer, G, Antequera, M, Antunez, C, Baquero, M, Bernal, M, Blesa, R, Buiza-Rueda, D, Bullido, MJ, Burguera, JA, Calero, M, Carrillo, F, Carrion-Claro, M, Casajeros, MJ, Clarimon, J, Cruz-Gamero, JM, de Pancorbo, MM, del Ser, T, Diez-Fairen, M, Fortea, J, Franco, E, Frank-Garcia, A, Garcia-Alberca, JM, Madrona, SG, Garcia-Ribas, G, Gomez-Garre, P, Hernandez, I, Hevilla, S, Jesus, S, Espinosa, MAL, Lage, C, Legaz, A, Lleo, A, de Munain, AL, Lopez-Garcia, S, Macias, D, Manzanares, S, Marin, M, Marin-Munoz, J, Marin, T, Montes, AM, Martinez, B, Martinez, C, Martinez, V, Alvarez, PML, Medina, M, Iriarte, MM, Menendez-Gonzalez, M, Mir, P, Molinuevo, JL, Pastor, AB, Pastor, P, Tur, JP, Perinan-Tocino, T, Ripoll, GP, Rabano, A, de Asua, DR, Rodrigo, S, Rodriguez-Rodriguez, E, Royo, JL, Diaz, RSD, Sanchez-Juan, P, Sastre, E, Sotolongo-Grau, O, Vicente, MP, Vivancos, L, GR ACE Consortium, DEGESCO Consortium, Alzheimers Dis Neuroimaging Initia.

ALZHEIMERS & DEMENTIA, 15, 1333-1347. 2019
The Marquesans at the fringes of the Austronesian expansion.
Palencia-Madrid, L, Baeta, M, Villaescusa, P, Nunez, C, de Pancorbo, MM, Luis, JR, Fadhlaoui-Zid, K, Somarelli, J, Garcia-Bertrand, R, Herrera, RJ.

EUROPEAN JOURNAL OF HUMAN GENETICS, 27, 801-810. 2019
Histomorphometric analysis of osteocyte lacunae in human and pig: exploring its potential for species discrimination..
Cummaudo M, Cappella A, Giacomini F, Raffone C, Màrquez-Grant N, Cattaneo C.

INTERNATIONAL JOURNAL OF LEGAL MEDICINE, 133, 711-718. 2019
Genetic variation of 17 X-chromosome STR loci in Tunisian population of Nabeul.
Messoussi, Monia, Prieto-Fernandez, Endika, Baeta, Miriam, Nunez, Carolina, Ben Ammar-El Gaaied, Amel, de Pancorbo, Marian M., Fadhlaoui-Zid, Karima.

INTERNATIONAL JOURNAL OF LEGAL MEDICINE, 133, 85-88. 2019
SOX2 expression diminishes with ageing in several tissues in mice and humans..
Carrasco-Garcia E, Moreno-Cugnon L, Garcia I, Borras C, Revuelta M, Izeta A, Lopez-Lluch G, de Pancorbo MM, Vergara I, Vina J, Matheu A.

Mechanisms of ageing and development, 177, 30-36. 2019
Effective resolution of the Y chromosome sublineages of the Iberian haplogroup R1b-DF27 with forensic purposes.
Villaescusa, P, Palencia-Madrid, L, Campaner, MA, Jauregui-Rada, J, Guerra-Rodriguez, M, Rocandio, AM, de Pancorbo, MM.

INTERNATIONAL JOURNAL OF LEGAL MEDICINE, 133, 17-23. 2019
Histomorphometric analysis of the variability of the human skeleton: Forensic implications..
Cummaudo M, Raffone C, Cappella A, Márquez-Grant N, Cattaneo C.

LEGAL MED-TOKYO, 45, 101711-101711.