Microfluidics Cluster UPV/EHU

Líneas de investigación

  • Microfluídica.
    • Desarrollo de dispositivos microfluídicos en papel, polímeros e híbridos.
    • Desarrollo de componentes microfluídicos modulares y estrategias para la integración.
  • Materiales inteligentes para detección y actuación.
    • Desarrollo de nuevos materiales sensores y actuadores.
    • Desarrollo de estrategias para la integración de materiales funcionales en sistemas microfluídicos.
  • Ingeniería de superficies.
    • Desarrollo de técnicas de diseño de superficies inteligentes. Integración de materiales y células para análisis.
  • Integración de microsistemas.
    • Desarrollo de nuevas estrategias para la integración de componentes de microsistemas.
    • Desarrollo de microsistemas con aplicación en los campos de la ciencia forense, análisis ambiental, biomedicina y deporte, entre otras.

Miembros del equipo

Mª LOURDES BASABE DESMONTS

Ikerbasque Research Prof.

FERNANDO BENITO LÓPEZ

Facultad de Farmacia 

JANIRE SÁEZ CASTAÑO

Facultad de Farmacia 

ENRIQUE AZUAJE HUALDE

Facultad de Farmacia 

Producción científica

A Conformable Organic Electronic Device for Monitoring Epithelial Integrity at the Air Liquid Interface.
Barron, SL, Oldroyd, SV, Saez, J, Chernaik, A, Guo, WR, Mccaughan, F, Bulmer, D, Owens, RM.

ADVANCED MATERIALS, , . 2024
DOI: 10.1002/adma.202306679
Cell Patterning Technology on Polymethyl Methacrylate through Controlled Physicochemical and Biochemical Functionalization.
Azuaje-Hualde, E., Komen, J., Alonso-Cabrera, J.A., van den Berg, A., De Pancorbo, M.M., van der Meer, A.D., Benito-Lopez, F., Basabe-Desmonts, L..

BIOSENSORS-BASEL, 13, . 2023
DOI: 10.3390/BIOS13100904
Method Based on Ultrafiltration to Obtain a Plasma Rich in Platelet and Plasma Growth Factors.
Mercader Ruiz, J., Beitia, M., Delgado, D., Sánchez, P., Guadilla, J., Pérez de Arrilucea, C., Benito-Lopez, F., Basabe-Desmonts, L., Sánchez, M..

Journal Of Clinical Medicine, 12, . 2023
DOI: 10.3390/JCM12185941
New Formulation of Platelet-Rich Plasma Enriched in Platelet and Extraplatelet Biomolecules Using Hydrogels.
Mercader Ruiz, J., Beitia, M., Delgado, D., Sánchez, P., Arnaiz, M.J., López de Dicastillo, L., Benito-Lopez, F., Basabe-Desmonts, L., Sánchez, M..

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 24, . 2023
DOI: 10.3390/IJMS241813811
Lab-in-a-Bead: Magnetic Janus Bead Probe for the Detection of Biomarkers in Blood.
Gunatilake, U.B., Caballe-Abalos, A., Garcia-Rey, S., Mercader-Ruiz, J., Basabe-Desmonts, L., Benito-Lopez, F..

ADVANCED MATERIALS INTERFACES, 10, . 2023
DOI: 10.1002/ADMI.202202459
The Importance of Dean Flow in Microfluidic Nanoparticle Synthesis: A ZIF-8 Case Study.
Yu, XJ, Andreo, J, Walden, M, del Campo, JF, Basabe-Desmonts, L, Benito-Lopez, F, Burg, TP, Wuttke, S.

Small Methods, 8, . 2023
DOI: 10.1002/smtd.202300603
3D organic bioelectronics for electrical monitoring of human adult stem cells.
Savva, A., Saez, J., Withers, A., Barberio, C., Stoeger, V., Elias-Kirma, S., Lu, Z., Moysidou, C.-M., Kallitsis, K., Pitsalidis, C., Owens, R.M..

MATERIALS HORIZONS, 10, 3589-3600. 2023
DOI: 10.1039/D3MH00785E
Capture and Release of Cancer Cells Through Smart Bioelectronics.
Saez, J., Garcia-Hernando, M., Savva, A., Owens, R.M., Benito-Lopez, F., Basabe-Desmonts, L..

Methods in molecular biology (Clifton, N.J.), 2679, 305-314. 2023
DOI: 10.1007/978-1-0716-3271-0_21
Development of an alginate/TiO2-based microfluidic biosystem for chrono-sampling and sensing of glucose in artificial sweat.
Garcia-Rey, S., Gil-Hernandez, E., Gunatilake, U.B., Basabe-Desmonts, L., Benito-Lopez, F..

SENSORS AND ACTUATORS B-CHEMICAL, 382, . 2023
DOI: 10.1016/J.SNB.2023.133514
Sustainable mold biomachining for the manufacturing of microfluidic devices.
Santaolalla, A, Alvarez-Braña, Y, Barona, A, Basabe-Desmonts, L, Benito-Lopez, F, Rojo, N.

JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY, 120, 332-339. 2023
DOI: 10.1016/j.jiec.2022.12.040
Precise Integration of Polymeric Sensing Functional Materials within 3D Printed Microfluidic Devices.
Etxebarria-Elezgarai, J., Garcia-Hernando, M., Basabe-Desmonts, L., Benito-Lopez, F..

Chemosensors, 11, . 2023
DOI: 10.3390/CHEMOSENSORS11040253
Magnetic Field Enhancement of Water Evaporation in Confined Spaces.
Poulose, S, Alvarez-Braña, Y, Basabel-Desmonts, L, Benito-Lopez, F, Coey, JMD.

IEEE MAGNETICS LETTERS, 14, . 2023
DOI: 10.1109/LMAG.2023.3262976
3D Organic Bioelectronics for Monitoring In Vitro Stem Cell Cultures.
SAEZ CASTAÑO, JANIRE.

BIORXIV, 486455, 1-18. 2023
DOI: 10.1101/2022.03.30.486455
Colorimetric Determination of Glucose in Sweat Using an Alginate-Based Biosystem.
Garcia-Rey, S., Gil-Hernandez, E., Basabe-Desmonts, L., Benito-Lopez, F..

POLYMERS, 15, . 2023
DOI: 10.3390/POLYM15051218
Microfluidics method isolates biomarkers after plasma separation.
Benito-López, F..

Biophotonics International, 30, 16-17. 2023
DOI:
Conducting Polymer-ECM Scaffolds for Human Neuronal Cell Differentiation.
Barberio, Chiara, Saez, Janire, Withers, Aimee, Nair, Malavika, Tamagnini, Francesco, Owens, Roisin M..

ADVANCED HEALTHCARE MATERIALS, 11, . 2022
DOI: 10.1002/adhm.202200941
High-Resolution 3D Printing Fabrication of a Microfluidic Platform for Blood Plasma Separation.
Garcia-Rey, S., Nielsen, J.B., Nordin, G.P., Woolley, A.T., Basabe-Desmonts, L., Benito-Lopez, F..

POLYMERS, 14, . 2022
DOI: 10.3390/POLYM14132537
Underwater magneto-driven air de-bubbler.
Gunatilake, U.B., Alvarez-Braña, Y., Ojeda, E., Basabe-Desmonts, L., Benito-Lopez, F..

JOURNAL OF MATERIALS CHEMISTRY A, 10, 12832-12841. 2022
DOI: 10.1039/D2TA01009G
A method for the controllable fabrication of optical fiber-based localized surface plasmon resonance sensors.
Calatayud-Sanchez, A., Ortega-Gomez, A., Barroso, J., Zubia, J., Benito-Lopez, F., Villatoro, J., Basabe-Desmonts, L..

SCIENTIFIC REPORTS, 12, . 2022
DOI: 10.1038/S41598-022-13707-Y
A 3D bioelectrical interface to assess colorectal cancer progression in vitro.
Saez, J., Dominguez-Alfaro, A., Barberio, C., Withers, A.M., Mecerreyes, D., Owens, R.M..

Materials Today Chemistry, 24, . 2022
DOI: 10.1016/J.MTCHEM.2022.100990
Ionogel-based hybrid polymer-paper handheld platform for nitrite and nitrate determination in water samples.
Catalan-Carrio, R., Saez, J., Fernández Cuadrado, L.Á., Arana, G., Basabe-Desmonts, L., Benito-Lopez, F..

ANALYTICA CHIMICA ACTA, 1205, . 2022
DOI: 10.1016/J.ACA.2022.339753
Paper based microfluidic platform for single-step detection of mesenchymal stromal cells secreted VEGF.
Azuaje-Hualde, E., De Pancorbo, M.M., Benito-Lopez, F., Basabe-Desmonts, L..

ANALYTICA CHIMICA ACTA, 1199, . 2022
DOI: 10.1016/J.ACA.2022.339588
Ex situ and in situ Magnetic Phase Synthesised Magneto-Driven Alginate Beads..
Bimendra Gunatilake U, Venkatesan M, Basabe-Desmonts L, Benito-Lopez F.

JOURNAL OF COLLOID AND INTERFACE SCIENCE, 610, 741-750. 2022
DOI: 10.1016/j.jcis.2021.11.119
Magneto Twister: Magneto Deformation of the Water-Air Interface by a Superhydrophobic Magnetic Nanoparticle Layer.
Gunatilake, U.B., Morales, R., Basabe-Desmonts, L., Benito-Lopez, F..

Langmuir, 38, 3360-3369. 2022
DOI: 10.1021/ACS.LANGMUIR.1C02925
Microfluidics and materials for smart water monitoring: A review..
Saez J, Catalan-Carrio R, Owens RM, Basabe-Desmonts L, Benito-Lopez F.

ANALYTICA CHIMICA ACTA, 1186, 338392-338392. 2021
DOI: 10.1016/j.aca.2021.338392
An electroactive and thermo-responsive material for the capture and release of cells.
Garcia-Hernando, M, Saez, J, Savva, A, Basabe-Desmonts, L, Owens, RM, Benito-Lopez, F.

BIOSENSORS & BIOELECTRONICS, 191, . 2021
DOI: 10.1016/j.bios.2021.113405
Alginate Bead Biosystem for the Determination of Lactate in Sweat Using Image Analysis..
Garcia-Rey S, Ojeda E, Gunatilake UB, Basabe-Desmonts L, Benito-Lopez F.

BIOSENSORS-BASEL, 11, . 2021
DOI: 10.3390/bios11100379
Modular micropumps fabricated by 3D printed technologies for polymeric microfluidic device applications.
Alvarez-Brana, Y, Etxebarria-Elezgarai, J, de Larrinaga-Vicente, LR, Benito-Lopez, F, Basabe-Desmonts, L.

SENSORS AND ACTUATORS B-CHEMICAL, 342, . 2021
DOI: 10.1016/j.snb.2021.129991
TiO 2 Nanotubes Alginate Hydrogel Scaffold for Rapid Sensing of Sweat Biomarkers: Lactate and Glucose..
Gunatilake UB, Garcia-Rey S, Ojeda E, Basabe-Desmonts L, Benito-Lopez F.

ACS APPLIED MATERIALS & INTERFACES, 13, 37734-37745. 2021
DOI: 10.1021/acsami.1c11446
Tunable Superparamagnetic Ring (tSPRing) for Droplet Manipulation.
Nasirimarekani, V, Benito-Lopez, F, Basabe-Desmonts, L.

ADVANCED FUNCTIONAL MATERIALS, 31, . 2021
DOI: 10.1002/adfm.202100178
Continuous monitoring of cell transfection efficiency with micropatterned substrates.
Azuaje-Hualde, E, Rosique, M, Calatayud-Sanchez, A, Benito-Lopez, F, de Pancorbo, MM, Basabe-Desmonts, L.

BIOTECHNOLOGY AND BIOENGINEERING, 118, 2626-2636. 2021
DOI: 10.1002/bit.27783
A microfluidic column of water index-matched packed microspheres for label-free observation of water pollutants.
Lanfranco, R, Saez, J, Abati, D, Carzaniga, T, Benito-Lopez, F, Buscaglia, M.

Microchimica Acta, 188, . 2021
DOI: 10.1007/s00604-021-04804-2
Cytochrome c detection by plasmonic nanospectroscopy on optical fiber facets.
Ortega-Gomez, A, Barroso, J, Calatayud-Sanchez, A, Zubia, J, Benito-Lopez, F, Basabe-Desmonts, L, Villatoro, J.

SENSORS AND ACTUATORS B-CHEMICAL, 330, . 2021
DOI: 10.1016/j.snb.2020.129358
Ionogel based material for the colorimetric detection of ?9-tetrahydrocannabinol.
CATALAN CARRIO, RAQUEL, MORENO SANZ, GUILLERMO, BENITO LOPEZ, FERNANDO, BASABE DESMONTS, LOURDES.

Proceedings of IEEE Sensors, , . 2021
DOI: 10.1109/SENSORS47087.2021.9639754
Large-Volume Self-Powered Disposable Microfluidics by the Integration of Modular Polymer Micropumps with Plastic Microfluidic Cartridges.
Etxebarria-Elezgarai, J, Alvarez-Brana, Y, Garoz-Sanchez, R, Benito-Lopez, F, Basabe-Desmonts, L.

INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, 59, 22485-22491. 2020
DOI: 10.1021/acs.iecr.0c03398
Predicting Dimensions in Microfluidic Paper Based Analytical Devices..
Catalan-Carrio R, Akyazi T, Basabe-Desmonts L, Benito-Lopez F.

SENSORS, 21, . 2020
DOI: 10.3390/s21010101
Advances in Microtechnology for Improved Cytotoxicity Assessment.
Garcia-Hernando, M, Benito-Lopez, F, Basabe-Desmonts, L.

Frontiers in Materials, 7, . 2020
DOI: 10.3389/fmats.2020.582030
Imidazole-based ionogel as room temperature benzene and formaldehyde sensor.
Gil-Gonzalez, N, Benito-Lopez, F, Castano, E, Morant-Minana, MC.

Microchimica Acta, 187, 638-638. 2020
DOI: 10.1007/s00604-020-04625-9
Microfluidic chip with pillar arrays for controlled production and observation of lipid membrane nanotubes.
Galvez, JMM, Garcia-Hernando, M, Benito-Lopez, F, Basabe-Desmonts, L, Shnyrova, AV.

Lab On A Chip, 20, 2748-2755. 2020
DOI: 10.1039/d0lc00451k
Naked eye Y amelogenin gene fragment detection using DNAzymes on a paper-based device.
Azuaje-Hualde, E, Arroyo-Jimenez, S, Garai-Ibabe, G, de Pancorbo, MM, Benito-Lopez, F, Basabe-Desmonts, L.

ANALYTICA CHIMICA ACTA, 1123, 1-8. 2020
DOI: 10.1016/j.aca.2020.05.010
Selective Ultrasensitive Optical Fiber Nanosensors Based on Plasmon Resonance Energy Transfer.
Barroso, J, Ortega-Gomez, A, Calatayud-Sanchez, A, Zubia, J, Benito-Lopez, F, Villatoro, J, Basabe-Desmonts, L.

Acs Sensors, 5, 2018-2024. 2020
DOI: 10.1021/acssensors.0c00418
Optical Single Cell Resolution Cytotoxicity Biosensor Based on Single Cell Adhesion Dot Arrays.
Garcia-Hernando, M, Calatayud-Sanchez, A, Etxebarria-Elezgarai, J, de Pancorbo, MM, Benito-Lopez, F, Basabe-Desmonts, L.

ANALYTICAL CHEMISTRY, 92, 9658-9665. 2020
DOI: 10.1021/acs.analchem.0c00940
Electrical and electrochemical properties of imidazolium and phosphonium-based pNIPAAM ionogels.
Gil-Gonzalez, N, Benito-Lopez, F, Castano, E, Morant-Minana, MC.

ELECTROCHIMICA ACTA, 345, . 2020
DOI: 10.1016/j.electacta.2020.136167
Silicon Microcantilever Sensors to Detect the Reversible Conformational Change of a Molecular Switch, Spiropyan.
Grogan, C, Amarandei, G, Lawless, S, Pedreschi, F, Lyng, F, Benito-Lopez, F, Raiteri, R, Florea, L.

SENSORS, 20, . 2020
DOI: 10.3390/s20030854
Extracellular matrix protein microarray-based biosensor with single cell resolution: Integrin profiling and characterization of cell-biomaterial interactions.
Gonzalez-Pujana, A, Santos-Vizcaino, E, Garcia-Hernando, M, Hernaez-Estrada, B, de Pancorbo, MM, Benito-Lopez, F, Igartua, M, Basabe-Desmonts, L, Hernandez, RM.

SENSORS AND ACTUATORS B-CHEMICAL, 299, . 2019
DOI: 10.1016/j.snb.2019.126954
Type 1 Diabetes Mellitus reversal via implantation of magnetically purified microencapsulated pseudoislets.
Espona-Noguera, A, Etxebarria-Elezgarai, J, del Burgo, LS, Canibano-Hernandez, A, Gurruchaga, H, Blanco, FJ, Orive, G, Hernandez, RM, Benito-Lopez, F, Ciriza, J, Basabe-Desmonts, L, Pedraz, JL.

INTERNATIONAL JOURNAL OF PHARMACEUTICS, 560, 65-77. 2019
DOI: 10.1016/j.ijpharm.2019.01.058